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DeCS
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Descriptor English:
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Signaling Lymphocytic Activation Molecule Family
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Descriptor Spanish:
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Familia de Moléculas Señalizadoras de la Activación Linfocitaria
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Descriptor Portuguese:
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Família de Moléculas de Sinalização da Ativação Linfocitária
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Synonyms English:
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SLAM Family Receptors
SLAMF Receptors
Signaling Lymphocytic Activation Molecule Family Receptors
Signaling Lymphocytic Activation Molecule Receptors
Signaling Lymphocytic Activation Molecules
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Tree Number:
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D12.776.395.550.736
D12.776.543.550.746
D12.776.543.750.705.970
D23.050.301.264.035.915
D23.101.100.110.935
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Definition English:
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Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56632
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Unique Identifier:
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D000071176
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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